Ok, as I have had my Kindle for a few weeks now I'd thought I'd weigh in on what I thought about it.
As for downloading books, book selections etc I'm over all happy.
With the Kindle itself?
Not so much in that with so many places on the sides to click, it doesn't leave much of an area for holding the device. I find I'm accidently turning pages. I also bought a leather cover to hold the Kindle, which pretty much makes the Kindle a hardcovered book and after a while the small bit of weight tends to get heavier and heavier as I hold it. As I mentioned earlier, I tried w/o the cover and then tended to hit the page turning buttons by accident as I was moving my hands to find different comfortable handholds.
The keyboard is a PITA as it's so small and you have to push fairly hard on the keys. It's a bit different than the normal keyboard for backspacing, caps etc so that gets frustrating.
I made my own collection headings so I can find my books under subject etc. Just when I think I remember how to move my books around, I tend to suddenly forget where/what button to click and the book ends up somewhere else and I have to go look for it. I'm putting this down to operator error and slowmindedness on my part....
Bottom line, I guess, is the Kindle itself could be less awkward to use, but that said, I am enjoying the art of reading again and perusing books albeit digitally.
PS on edit: I just checked at AMazon and it looks like Kindle has come out with an all new look? Perhaps I'm not the only one complaining?