Jan, Like the others have said the HAM operators are much more regulated and respectful of their privilege to have that license, whereas lots of CBers don't really care because they can get away with it easier (unless someone reports them to the FCC).
As Nancy said you will probably be on a little used channel just to talk between yourselves, BUT, if you use Channel 19 which in most places is the trucker's channel (somewhere we were it was 17) you will have the road info for any problems ahead.
Just a few things you might want to learn is of course 10-4 is okay, 10-100 is potty break, 10-200, well, that is just too much information and you can just go with the 10-100 and that should cover it
Don't call anybody "Good Buddy" as it doesn't mean what it used to, now days a trucker may meet a "Good Buddy" in the back of a truck stop parking lot or dark rest area, if you know what I mean. BUT, if you should forget and call a trucker that, when you see his big rig next to you, glaring at ya through the window, here's what'cha do,
#1 Quickly point at yourself while shaking your head NO
#2 Point at the rig in front of you while remembering how all the pics you tried to snap while driving, of the beautiful scenery, has the back side of their rig right smack in the middle of all your pics. And how they volunteered "Oh, me and Jan will bring up the rear of the caravan" and they ran right through the light as it turned red and you knew there were 5 turn offs coming up,,,(sorry, I had to stop and laugh a minute, whew, okay I'm ready) and you were left behind,,, just go ahead and point at them and mouth the words "bad, bad person"
Then get out of the way!
And unless you're in the south, if someone says on the CB that there's alligators in the road up ahead, don't bother grabbing your camera, it's just pieces of tires on the road and anyway, your pics would just have the rear end of the rig up ahead of ya anyway!